STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
USP36Ubiquitin specific peptidase 36; Belongs to the peptidase C19 family. (1123 aa)    
Predicted Functional Partners:
DHX33
DEAH-box helicase 33.
    
 
 0.757
UTP14A
UTP14A small subunit processome component.
   
 
 0.595
ZUP1
Zinc finger with UFM1-specific peptidase domain.
      
 0.592
SUDS3
SDS3 homolog, SIN3A corepressor complex component.
    
 0.510
ATG14
ATG14 autophagy related 14 homolog.
      
 0.509
RB1CC1
RB1-inducible coiled-coil 1.
      
 0.493
LAMP1
Lysosome-associated membrane glycoprotein 1.
      
 0.486
WDFY3
WD repeat and FYVE domain containing 3.
      
 0.485
MYC
Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity).
    
 
 0.484
H2BC21
HIST2H2BE isoform 1.
   
 
 0.483
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
Server load: medium (62%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.