STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
P4HBProtein disulfide-isomerase. (508 aa)    
Predicted Functional Partners:
ERO1A
Endoplasmic reticulum oxidoreductase 1 alpha.
   
 0.993
MTTP
Microsomal triglyceride transfer protein.
   
 0.989
P4HA2
Prolyl 4-hydroxylase, alpha polypeptide II.
   
 0.988
CALR
Calreticulin.
   
 0.985
ERO1B
ERO1-like protein beta.
   
 0.985
HSPA5
Heat shock 70kDa protein 5 (Glucose-regulated protein, 78kDa); Belongs to the heat shock protein 70 family.
   
 0.954
LOC100609513
78 kDa glucose-regulated protein pseudogene.
   
 0.945
P4HA1
Prolyl 4-hydroxylase, alpha polypeptide I.
   
 0.929
PPIB
Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
   
 0.925
P4HA3
P4HA3 isoform 4.
   
 0.871
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.