GREB1 protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CREBBP	EP300	ENSPTRP00000074980	ENSPTRP00000024841	CREB binding protein.	E1A binding protein p300.	0.999
CREBBP	ESR1	ENSPTRP00000074980	ENSPTRP00000031932	CREB binding protein.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.971
CREBBP	ESR2	ENSPTRP00000074980	ENSPTRP00000010911	CREB binding protein.	Estrogen receptor 2.	0.826
CREBBP	GREB1	ENSPTRP00000074980	ENSPTRP00000016851	CREB binding protein.	Growth regulating estrogen receptor binding 1.	0.920
CREBBP	PGR	ENSPTRP00000074980	ENSPTRP00000007237	CREB binding protein.	Progesterone receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcriptional activator of several progesteron-dependent promoters in a variety of cell types. Involved in activation of SRC-dependent MAPK signaling on hormone stimulation.	0.581
CYP19A1	ESR1	ENSPTRP00000012092	ENSPTRP00000031932	Cytochrome P450 family 19 subfamily A member 1; Belongs to the cytochrome P450 family.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.806
CYP19A1	ESR2	ENSPTRP00000012092	ENSPTRP00000010911	Cytochrome P450 family 19 subfamily A member 1; Belongs to the cytochrome P450 family.	Estrogen receptor 2.	0.765
CYP19A1	GREB1	ENSPTRP00000012092	ENSPTRP00000016851	Cytochrome P450 family 19 subfamily A member 1; Belongs to the cytochrome P450 family.	Growth regulating estrogen receptor binding 1.	0.575
CYP19A1	PGR	ENSPTRP00000012092	ENSPTRP00000007237	Cytochrome P450 family 19 subfamily A member 1; Belongs to the cytochrome P450 family.	Progesterone receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcriptional activator of several progesteron-dependent promoters in a variety of cell types. Involved in activation of SRC-dependent MAPK signaling on hormone stimulation.	0.626
CYP19A1	WNT4	ENSPTRP00000012092	ENSPTRP00000063328	Cytochrome P450 family 19 subfamily A member 1; Belongs to the cytochrome P450 family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.634
EP300	CREBBP	ENSPTRP00000024841	ENSPTRP00000074980	E1A binding protein p300.	CREB binding protein.	0.999
EP300	ESR1	ENSPTRP00000024841	ENSPTRP00000031932	E1A binding protein p300.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.981
EP300	ESR2	ENSPTRP00000024841	ENSPTRP00000010911	E1A binding protein p300.	Estrogen receptor 2.	0.868
EP300	GREB1	ENSPTRP00000024841	ENSPTRP00000016851	E1A binding protein p300.	Growth regulating estrogen receptor binding 1.	0.887
EP300	PGR	ENSPTRP00000024841	ENSPTRP00000007237	E1A binding protein p300.	Progesterone receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcriptional activator of several progesteron-dependent promoters in a variety of cell types. Involved in activation of SRC-dependent MAPK signaling on hormone stimulation.	0.715
ESR1	CREBBP	ENSPTRP00000031932	ENSPTRP00000074980	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	CREB binding protein.	0.971
ESR1	CYP19A1	ENSPTRP00000031932	ENSPTRP00000012092	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Cytochrome P450 family 19 subfamily A member 1; Belongs to the cytochrome P450 family.	0.806
ESR1	EP300	ENSPTRP00000031932	ENSPTRP00000024841	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	E1A binding protein p300.	0.981
ESR1	ESR2	ENSPTRP00000031932	ENSPTRP00000010911	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Estrogen receptor 2.	0.999
ESR1	GREB1	ENSPTRP00000031932	ENSPTRP00000016851	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Growth regulating estrogen receptor binding 1.	0.941