STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ESCO1Establishment of sister chromatid cohesion N-acetyltransferase 1. (840 aa)    
Predicted Functional Partners:
SMC3
Structural maintenance of chromosomes protein.
   
 0.968
PDS5A
PDS5, regulator of cohesion maintenance, homolog A.
   
 0.935
RAD21
RAD21 cohesin complex component.
   
 0.888
WAPL
WAPL cohesin release factor.
   
 
 0.863
STAG1
Stromal antigen 1.
   
 0.818
SMC2
Structural maintenance of chromosomes protein.
   
 0.814
PDS5B
PDS5, regulator of cohesion maintenance, homolog B.
   
 0.813
SMC1A
Structural maintenance of chromosomes protein.
   
 0.809
SMC4
Structural maintenance of chromosomes protein.
   
 0.799
CHTF18
CTF18, chromosome transmission fidelity factor 18 homolog.
   
 
 0.788
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.