STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABHD3Abhydrolase domain containing 3. (409 aa)    
Predicted Functional Partners:
CABLES1
Cdk5 and Abl enzyme substrate 1.
      
 0.733
THOC1
THOC1 isoform 2.
      
 0.704
USP14
Ubiquitin carboxyl-terminal hydrolase 14; Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin at the proteasome. Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell. Required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis. Serves also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibi [...]
   
  
 0.615
TRPC4AP
Transient receptor potential cation channel, subfamily C, member 4 associated protein.
      
 0.478
ABHD4
Abhydrolase domain containing 4.
   
 
 0.476
ABHD6
Abhydrolase domain containing 6.
   
 
 0.474
ATRAID
All-trans retinoic acid induced differentiation factor.
      
 0.472
EEF1AKNMT
METTL13 isoform 4.
      
 0.469
PLPP6
Phosphatidic acid phosphatase type 2 domain containing 2.
      
 0.467
ABHD16A
Abhydrolase domain containing 16A.
      
 0.465
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.