STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMAD4Mothers against decapentaplegic homolog. (552 aa)    
Predicted Functional Partners:
SMAD2
Mothers against decapentaplegic homolog.
   
0.999
SMAD3
Mothers against decapentaplegic homolog.
   
0.999
SMAD1
Mothers against decapentaplegic homolog.
   
0.998
SMAD9
Mothers against decapentaplegic homolog.
   
0.997
SMAD5
Mothers against decapentaplegic homolog.
   
0.994
SKI
V-ski sarcoma viral oncogene homolog (Avian).
   
 0.992
TGFBR1
Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
   
 0.991
E2F4
E2F transcription factor 4, p107/p130-binding.
    
 0.990
LEF1
Lymphoid enhancer binding factor 1.
   
 0.984
E2F5
E2F transcription factor 5.
    
 0.982
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.