STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LMAN1Lectin, mannose-binding, 1. (510 aa)    
Predicted Functional Partners:
MCFD2
Multiple coagulation factor deficiency 2.
   
 0.999
SEC31A
SEC31 homolog A, COPII coat complex component.
   
 
 0.848
SEC24C
SEC24 homolog C, COPII coat complex component.
   
 
 0.846
CK820_G0056867
SEC22B isoform 1; Belongs to the synaptobrevin family.
   
 0.826
F8
Coagulation factor VIII; Belongs to the multicopper oxidase family.
    
 0.820
SEC16A
Protein transport protein sec16; Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus.
     
 0.817
SEC23A
Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.
   
 
 0.790
SEC13
SEC13 isoform 7; Belongs to the WD repeat SEC13 family.
   
 
 0.784
PREB
Prolactin regulatory element binding.
   
 0.782
SEC24B
SEC24B isoform 1.
   
 
 0.767
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.