STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KDSR3-ketodihydrosphingosine reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (332 aa)    
Predicted Functional Partners:
SPTLC2
Serine palmitoyltransferase, long chain base subunit 2.
     
 0.980
SPTLC3
Serine palmitoyltransferase, long chain base subunit 3.
     
 0.979
DEGS1
Degenerative spermatocyte homolog 1, lipid desaturase.
   
 
 0.956
CERS2
LAG1 homolog, ceramide synthase 2.
     
 0.954
CERS6
Ceramide synthase 6.
     
 0.954
CERS3
CERS3 isoform 1.
     
 0.953
DEGS2
Delta 4-desaturase, sphingolipid 2.
   
 
 0.950
SPHK2
Sphingosine kinase 2.
     
 0.949
SPHK1
Sphingosine kinase 1.
     
 0.949
CERS4
CERS4 isoform 1.
     
 0.941
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
Server load: medium (60%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.