STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ELANEElastase, neutrophil expressed. (267 aa)    
Predicted Functional Partners:
CTSG
CTSG isoform 2; Belongs to the peptidase S1 family.
  
0.999
MPO
Myeloperoxidase.
   
 0.999
AZU1
AZU1 isoform 1.
  
 
0.999
DEFA4
Neutrophil defensin 4; Has antimicrobial activity against Gram-negative bacteria, and to a lesser extent also against Gram-positive bacteria and fungi. Inhibits corticotropin (ACTH)-stimulated corticosterone production (By similarity).
   
 
 0.999
SLPI
Secretory leukocyte peptidase inhibitor.
    
 0.975
PRTN3
PRTN3 isoform 2.
  
 
0.970
SERPINA1
Serpin family A member 1; Belongs to the serpin family.
    
 0.969
BPI
Bactericidal permeability increasing protein.
   
 
 0.932
CAMP
Cathelicidin antimicrobial peptide; Binds to bacterial lipopolysaccharides (LPS), has antibacterial activity; Belongs to the cathelicidin family.
   
 
 0.899
CEACAM8
Carcinoembryonic antigen related cell adhesion molecule 8.
   
 0.895
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.