STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PEAK3PEAK family member 3. (473 aa)    
Predicted Functional Partners:
FAM20A
FAM20A golgi associated secretory pathway pseudokinase.
      
 0.828
STKLD1
Serine/threonine kinase like domain containing 1.
      
 0.756
TRRAP
Transformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family.
      
 0.734
PAN3
PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA deca [...]
      
 0.719
SELENOO
SELENOO isoform 1.
      
 0.691
PSKH2
Protein serine kinase H2.
      
 0.661
ITSN2
ITSN2 isoform 1.
     
 0.605
KSR1
KSR1 isoform 4.
    
 0.485
RND2
Rho family GTPase 2.
     
 0.485
C22H22orf31
Chromosome 22 C22orf31 homolog.
  
     0.477
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.