STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NCLNNicalin; May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning. (563 aa)    
Predicted Functional Partners:
TMEM147
Transmembrane protein 147.
    
 
 0.960
CCDC47
Coiled-coil domain containing 47.
    
 
 0.888
TMCO1
Transmembrane and coiled-coil domains 1.
   
 
 0.878
SEC61A1
SEC61 translocon alpha 1 subunit.
   
 
 0.832
RPL19
Ribosomal protein L19; Belongs to the eukaryotic ribosomal protein eL19 family.
    
   0.797
SEC61B
Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.
    
   0.772
RPL11
Ribosomal protein L11; Belongs to the universal ribosomal protein uL5 family.
    
 
 0.764
RPL36AL
RPL36AL isoform 1; Belongs to the eukaryotic ribosomal protein eL42 family.
    
   0.757
RPL23
Ribosomal protein L23; Belongs to the universal ribosomal protein uL14 family.
    
   0.757
SEC61G
SEC61 translocon gamma subunit.
    
   0.757
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.