STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SH3GL1SH3 domain containing GRB2 like 1, endophilin A2. (368 aa)    
Predicted Functional Partners:
GAK
Cyclin G associated kinase.
   
 0.929
CBL
Cas-Br-M (Murine) ecotropic retroviral transforming sequence.
    
 0.910
SH3GL2
SH3 domain containing GRB2 like 2, endophilin A1.
  
 
 
0.882
SH3GL3
SH3 domain containing GRB2 like 3, endophilin A3.
  
 
 
0.881
CBLB
Cas-Br-M (Murine) ecotropic retroviral transforming sequence b.
    
 0.881
CBLC
Cbl proto-oncogene C.
    
 0.875
PDCD6IP
Programmed cell death 6 interacting protein.
   
 
 0.832
ARHGAP8
PRR5-ARHGAP8 isoform 3.
    
 
 0.818
EGFR
Receptor protein-tyrosine kinase.
    
 0.806
SYNJ2
SYNJ2 isoform 1.
    
 
 0.781
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.