STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEMA6BSema domain, transmembrane domain (TM), and cytoplasmic domain, (Semaphorin) 6B; Belongs to the semaphorin family. (888 aa)    
Predicted Functional Partners:
SEMA6C
SEMA6C isoform 2; Belongs to the semaphorin family.
     
0.907
SEMA6A
SEMA6A isoform 2; Belongs to the semaphorin family.
     
0.903
PLXNA2
PLXNA2 isoform 1.
    
 0.894
PLXNA4
PLXNA4 isoform 1.
    
0.807
PLXNA3
PLXNA3 isoform 1.
    
 0.796
NRP1
Neuropilin; Belongs to the neuropilin family.
    
 0.678
PLXNA1
PLXNA1 isoform 1.
    
 0.677
EVL
Enah/Vasp-like; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family.
    
 
 0.674
MST1R
Macrophage stimulating 1 receptor.
    
 0.650
PLXNB1
PLXNB1 isoform 1.
    
0.632
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
Server load: medium (50%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.