STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEMA6BSema domain, transmembrane domain (TM), and cytoplasmic domain, (Semaphorin) 6B; Belongs to the semaphorin family. (888 aa)    
Predicted Functional Partners:
ALK
Tyrosine-protein kinase receptor.
   
  0.994
PNPT1
Polyribonucleotide nucleotidyltransferase 1.
   
    0.975
ENSPTRP00000068740
annotation not available
   
    0.879
PLXNA2
PLXNA2 isoform 1.
    
 0.800
PLXNA3
PLXNA3 isoform 1.
    
 0.761
PLXNA1
PLXNA1 isoform 1.
    
 0.706
NRP1
Neuropilin; Belongs to the neuropilin family.
    
 0.675
PLXNB1
PLXNB1 isoform 1.
    
 0.641
CELSR2
CELSR2 isoform 1; Belongs to the G-protein coupled receptor 2 family.
      
 0.639
PRICKLE2
Prickle planar cell polarity protein 2.
      
 0.631
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.