| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CFTR | MARCH2 | ENSPTRP00000033597 | ENSPTRP00000017735 | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] | Membrane-associated ring finger (C3HC4) 2. | 0.629 |
| KHNYN | MARCH2 | ENSPTRP00000010562 | ENSPTRP00000017735 | KH and NYN domain containing. | Membrane-associated ring finger (C3HC4) 2. | 0.566 |
| KHNYN | MARCHF1 | ENSPTRP00000010562 | ENSPTRP00000028432 | KH and NYN domain containing. | MARCH1 isoform 3. | 0.500 |
| MARCH2 | CFTR | ENSPTRP00000017735 | ENSPTRP00000033597 | Membrane-associated ring finger (C3HC4) 2. | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] | 0.629 |
| MARCH2 | KHNYN | ENSPTRP00000017735 | ENSPTRP00000010562 | Membrane-associated ring finger (C3HC4) 2. | KH and NYN domain containing. | 0.566 |
| MARCH2 | MARCHF1 | ENSPTRP00000017735 | ENSPTRP00000028432 | Membrane-associated ring finger (C3HC4) 2. | MARCH1 isoform 3. | 0.665 |
| MARCH2 | MARCHF5 | ENSPTRP00000017735 | ENSPTRP00000046954 | Membrane-associated ring finger (C3HC4) 2. | MARCH5 isoform 1. | 0.627 |
| MARCH2 | MARCHF8 | ENSPTRP00000017735 | ENSPTRP00000075641 | Membrane-associated ring finger (C3HC4) 2. | Membrane associated ring-CH-type finger 8. | 0.774 |
| MARCH2 | SERINC3 | ENSPTRP00000017735 | ENSPTRP00000023229 | Membrane-associated ring finger (C3HC4) 2. | Serine incorporator 3. | 0.681 |
| MARCH2 | STX6 | ENSPTRP00000017735 | ENSPTRP00000042368 | Membrane-associated ring finger (C3HC4) 2. | STX6 isoform 2; Belongs to the syntaxin family. | 0.759 |
| MARCH2 | TGOLN2 | ENSPTRP00000017735 | ENSPTRP00000020807 | Membrane-associated ring finger (C3HC4) 2. | Trans-golgi network protein 2. | 0.557 |
| MARCH2 | UBR1 | ENSPTRP00000017735 | ENSPTRP00000011934 | Membrane-associated ring finger (C3HC4) 2. | E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. | 0.518 |
| MARCH2 | UBR2 | ENSPTRP00000017735 | ENSPTRP00000061650 | Membrane-associated ring finger (C3HC4) 2. | E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. | 0.506 |
| MARCHF1 | KHNYN | ENSPTRP00000028432 | ENSPTRP00000010562 | MARCH1 isoform 3. | KH and NYN domain containing. | 0.500 |
| MARCHF1 | MARCH2 | ENSPTRP00000028432 | ENSPTRP00000017735 | MARCH1 isoform 3. | Membrane-associated ring finger (C3HC4) 2. | 0.665 |
| MARCHF1 | UBR1 | ENSPTRP00000028432 | ENSPTRP00000011934 | MARCH1 isoform 3. | E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. | 0.412 |
| MARCHF1 | UBR2 | ENSPTRP00000028432 | ENSPTRP00000061650 | MARCH1 isoform 3. | E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. | 0.409 |
| MARCHF5 | MARCH2 | ENSPTRP00000046954 | ENSPTRP00000017735 | MARCH5 isoform 1. | Membrane-associated ring finger (C3HC4) 2. | 0.627 |
| MARCHF5 | MARCHF8 | ENSPTRP00000046954 | ENSPTRP00000075641 | MARCH5 isoform 1. | Membrane associated ring-CH-type finger 8. | 0.467 |
| MARCHF8 | MARCH2 | ENSPTRP00000075641 | ENSPTRP00000017735 | Membrane associated ring-CH-type finger 8. | Membrane-associated ring finger (C3HC4) 2. | 0.774 |
