STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDKN2DCyclin dependent kinase inhibitor 2D. (166 aa)    
Predicted Functional Partners:
CDK6
Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily.
    
 0.999
CDK4
Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily.
    
 0.998
CCND3
CCND3 isoform 1; Belongs to the cyclin family.
    
 0.967
CCND2
CCND2 isoform 1; Belongs to the cyclin family.
    
 0.960
CCND1
CCND1 isoform 1; Belongs to the cyclin family.
    
 0.953
CDK2
CDK2 isoform 4; Belongs to the protein kinase superfamily.
    
 0.814
CDKN1B
Cyclin-dependent kinase inhibitor 1B (P27, Kip1).
    
 0.746
CDKN1C
CDKN1C isoform 1.
    
 0.678
CDKN1A
Cyclin-dependent kinase inhibitor 1A (P21, Cip1).
    
 0.662
CCNL2
CCNL2 isoform 3; Belongs to the cyclin family.
      
 0.651
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.