STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAB3DRAB3D, member RAS oncogene family. (219 aa)    
Predicted Functional Partners:
RIMS2
Regulating synaptic membrane exocytosis 2.
    
 0.937
SYT2
Synaptotagmin 2.
   
 0.740
STX11
STX11 isoform 1; Belongs to the syntaxin family.
    
 0.716
SYT8
Synaptotagmin 8.
   
 0.712
VAMP5
Vesicle-associated membrane protein 5 (Myobrevin).
   
 
 0.705
SYT1
Synaptotagmin 1.
   
 0.668
SYT4
Synaptotagmin 4.
   
 0.662
SNAP25
Synaptosomal-associated protein 25; t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF. Modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 in pancreatic beta cells; Belongs to the SNAP-25 family.
   
 0.658
SYT11
Synaptotagmin 11.
   
 0.656
RABGGTA
Rab geranylgeranyltransferase, alpha subunit.
    
 0.650
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.