STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NANOS3NANOS3 isoform 4; Belongs to the nanos family. (192 aa)    
Predicted Functional Partners:
DAZL
RRM domain-containing protein.
    
 
 0.729
ATAT1
Alpha-tubulin N-acetyltransferase 1; Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dyn [...]
      
 0.716
MSH5
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
      
 0.716
TSN
TSN isoform 1.
      
 0.662
RBM44
RNA binding motif protein 44.
      
 0.662
SYCE2
Synaptonemal complex central element protein 2.
      
 0.655
GDPD2
Glycerophosphodiester phosphodiesterase domain containing 2.
      
 0.651
PUM2
Pumilio RNA binding family member 2.
   
 
 0.631
PUM1
PUM1 isoform 1.
   
 
 0.626
TDRD5
Tudor domain containing 5.
   
  
 0.619
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.