STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CC2D1ACoiled-coil and C2 domain containing 1A. (951 aa)    
Predicted Functional Partners:
CHMP4C
Charged multivesicular body protein 4C.
    
 0.875
CK820_G0048024
CHMP6 isoform 1.
     
 0.826
KCNH3
Potassium voltage-gated channel subfamily H member 3.
      
 0.818
ZNF286A
Zinc finger protein 286A.
      
 0.813
HOXD1
HOXD1 isoform 1.
      
 0.786
ZNF24
Zinc finger protein 24; Transcription factor required for myelination of differentiated oligodendrocytes. Required for the conversion of oligodendrocytes from the premyelinating to the myelinating state. In the developing central nervous system (CNS), involved in the maintenance in the progenitor stage by promoting the cell cycle. Specifically binds to the 5'-TCAT-3' DNA sequence. Has transcription repressor activity in vitro (By similarity).
      
 0.763
ZNF331
Zinc finger protein 331.
      
 0.763
VPS4A
Vacuolar protein sorting 4 homolog A; Belongs to the AAA ATPase family.
     
 0.757
CHMP2A
Charged multivesicular body protein 2A.
     
 0.747
VPS4B
Vacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family.
     
 0.747
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.