STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IL27RAInterleukin 27 receptor subunit alpha. (554 aa)    
Predicted Functional Partners:
ENSPTRP00000013548
Interleukin 27.
    
 0.980
JAK1
Tyrosine-protein kinase.
    
 0.953
JAK2
Tyrosine-protein kinase.
    
 0.944
IL12RB1
IL12RB1 isoform 1.
  
 
 0.935
CNTFR
CNTFR isoform 1.
   
 0.931
IL6R
Interleukin 6 receptor.
   
 0.833
CNTF
Ciliary neurotrophic factor.
    
 0.792
IL6
Interleukin 6 (Interferon, beta 2).
    
 0.788
IL6-2
Interleukin 6.
    
 0.788
STAT1
Signal transducer and activator of transcription.
    
 0.769
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.