STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRKACAPRKACA isoform 7; Belongs to the protein kinase superfamily. (289 aa)    
Predicted Functional Partners:
PRKAR1A
Protein kinase, cAMP-dependent, regulatory, type I, alpha (Tissue specific extinguisher 1).
 
 
 0.999
PRKAR2B
Protein kinase, cAMP-dependent, regulatory, type II, beta.
 
 
 0.999
PRKAR1B
Protein kinase cAMP-dependent type I regulatory subunit beta.
 
 
 0.999
PRKAR2A
Protein kinase cAMP-dependent type II regulatory subunit alpha.
 
 
 0.997
PKIA
cAMP-dependent protein kinase inhibitor; Belongs to the PKI family.
   
 0.993
AKAP1
A-kinase anchoring protein 1.
    
 0.989
RELA
V-rel reticuloendotheliosis viral oncogene homolog A (Avian).
   
 0.987
PRKACB
Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.
  
 
 
0.984
RYR2
RYR2 isoform 1.
    
 0.983
PDE4A
Phosphodiesterase.
   
 0.983
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.