STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GIPC1GIPC1 isoform 3. (333 aa)    
Predicted Functional Partners:
MYO6
MYO6 isoform 3; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
    
 
 0.988
RGS19
Regulator of G-protein signaling 19.
    
 
 0.929
NRP1
Neuropilin; Belongs to the neuropilin family.
    
 
 0.894
APPL1
Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1.
   
 
 0.872
LRP2
LRP2 isoform 1.
    
 
 0.814
ARHGEF12
Rho guanine nucleotide exchange factor (GEF) 12.
    
 
 0.810
SDC4
Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.
    
 
 0.780
PLXND1
PLXND1 isoform 1.
    
 
 0.755
TAX1BP3
Tax1-binding protein 3; May regulate a number of protein-protein interactions by competing for PDZ domain binding sites.
      
 0.696
APPL2
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.
   
 
 0.676
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.