STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DNAJB1DnaJ heat shock protein family (Hsp40) member B1. (340 aa)    
Predicted Functional Partners:
HSPA4
Heat shock protein family A (Hsp70) member 4.
 
 0.993
HSP90AB1
HSP90AB1 isoform 1.
  
 0.970
HSP90AA1
Heat shock protein HSP 90-alpha; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a ra [...]
  
 0.970
DNAJC3
DnaJ heat shock protein family (Hsp40) member C3.
   
0.961
HSPH1
HSPH1 isoform 3.
 
 0.957
LOC745166
HSPA1A isoform 1; Belongs to the heat shock protein 70 family.
 
 0.937
MAPKAPK5
Mitogen-activated protein kinase-activated protein kinase 5.
   
 
 0.928
ENSPTRP00000089678
annotation not available
 
 0.916
ENSPTRP00000062406
annotation not available
 
 0.915
HSPA8
Heat shock protein family A (Hsp70) member 8; Belongs to the heat shock protein 70 family.
 
 0.915
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.