STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NOTCH3NOTCH3 isoform 1. (2321 aa)    
Predicted Functional Partners:
JAG1
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
   
0.998
DLL1
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
    
0.998
RBPJ
Recombination signal binding protein for immunoglobulin kappa J region.
    
 0.998
JAG2
Jagged canonical Notch ligand 2.
   
0.983
MAML1
MAML1 isoform 1.
   
 0.981
DLL4
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
    
0.981
MAML3
MAML3 isoform 1.
    
 0.974
MAML2
Mastermind like transcriptional coactivator 2.
    
 0.968
DLL3
Delta like canonical Notch ligand 3.
     
0.965
DTX1
Deltex E3 ubiquitin ligase 1.
    
 0.958
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.