STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HSH2DHSH2D isoform 1. (352 aa)    
Predicted Functional Partners:
GPR32
G protein-coupled receptor 32.
   
  
 0.663
ANXA1
Annexin A1; Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity. Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. Promotes resolution of inflammation and wound healing (By similarity). Functions at least in part by activating the formyl peptide receptors and downstream signaling cascades. Promotes chemotaxis of granulocytes and monocytes via activation of Fthe formyl peptide receptors (By similarity). Contribu [...]
      
 0.661
CMKLR1
Chemerin chemokine-like receptor 1; Belongs to the G-protein coupled receptor 1 family.
   
  
 0.582
TNK2-2
Tyrosine kinase non receptor 2.
    
 
 0.568
TNK2
TNK2 isoform 2; Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 
 0.568
LTB4R
Leukotriene B4 receptor; Belongs to the G-protein coupled receptor 1 family.
      
 0.565
ALB
ALB isoform 2.
      
 0.457
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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