STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LRP3Low density lipoprotein receptor-related protein 3. (770 aa)    
Predicted Functional Partners:
DOC2B
Double C2-like domain-containing protein.
   
  
 0.691
LRPAP1
Low density lipoprotein receptor-related protein associated protein 1.
    
 
 0.630
LDLRAD2
Low density lipoprotein receptor class A domain containing 2.
      
 0.621
ITSN2
ITSN2 isoform 1.
    
 0.614
NOXA1
NOXA1 isoform 2.
    
 0.592
APOE
Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...]
    
 0.513
RELN
RELN isoform 3.
    
 0.511
CTNNA3
CTNNA3 isoform 1.
   
  
 0.487
ABCG5
ATP binding cassette subfamily G member 5.
    
 
 0.487
APLP1
APLP1 isoform 2.
    
 0.481
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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