TYROBP protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AIF1	CSF1R	ENSPTRP00000030665	ENSPTRP00000080883	Allograft inflammatory factor 1.	Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.613
AIF1	FCER1G	ENSPTRP00000030665	ENSPTRP00000051638	Allograft inflammatory factor 1.	Fc fragment of IgE receptor Ig.	0.876
AIF1	ITGB2	ENSPTRP00000030665	ENSPTRP00000091175	Allograft inflammatory factor 1.	Integrin beta.	0.740
AIF1	TREM2	ENSPTRP00000030665	ENSPTRP00000031017	Allograft inflammatory factor 1.	Triggering receptor expressed on myeloid cells 2.	0.535
AIF1	TYROBP	ENSPTRP00000030665	ENSPTRP00000018632	Allograft inflammatory factor 1.	TYRO protein tyrosine kinase-binding protein; Adapter protein which non-covalently associates with activating receptors found on the surface of a variety of immune cells to mediate signaling and cell activation following ligand binding by the receptors (By similarity). TYROBP is tyrosine-phosphorylated in the ITAM domain following ligand binding by the associated receptors which leads to activation of additional tyrosine kinases and subsequent cell activation (By similarity). Also has an inhibitory role in some cells (By similarity). Non-covalently associates with activating receptors [...]	0.944
CD300LB	CD300LF	ENSPTRP00000016328	ENSPTRP00000016340	CD300 molecule like family member b.	CD300 molecule like family member f.	0.737
CD300LB	FCER1G	ENSPTRP00000016328	ENSPTRP00000051638	CD300 molecule like family member b.	Fc fragment of IgE receptor Ig.	0.446
CD300LB	TREM2	ENSPTRP00000016328	ENSPTRP00000031017	CD300 molecule like family member b.	Triggering receptor expressed on myeloid cells 2.	0.474
CD300LB	TYROBP	ENSPTRP00000016328	ENSPTRP00000018632	CD300 molecule like family member b.	TYRO protein tyrosine kinase-binding protein; Adapter protein which non-covalently associates with activating receptors found on the surface of a variety of immune cells to mediate signaling and cell activation following ligand binding by the receptors (By similarity). TYROBP is tyrosine-phosphorylated in the ITAM domain following ligand binding by the associated receptors which leads to activation of additional tyrosine kinases and subsequent cell activation (By similarity). Also has an inhibitory role in some cells (By similarity). Non-covalently associates with activating receptors [...]	0.901
CD300LF	CD300LB	ENSPTRP00000016340	ENSPTRP00000016328	CD300 molecule like family member f.	CD300 molecule like family member b.	0.737
CD300LF	FCER1G	ENSPTRP00000016340	ENSPTRP00000051638	CD300 molecule like family member f.	Fc fragment of IgE receptor Ig.	0.512
CD300LF	TYROBP	ENSPTRP00000016340	ENSPTRP00000018632	CD300 molecule like family member f.	TYRO protein tyrosine kinase-binding protein; Adapter protein which non-covalently associates with activating receptors found on the surface of a variety of immune cells to mediate signaling and cell activation following ligand binding by the receptors (By similarity). TYROBP is tyrosine-phosphorylated in the ITAM domain following ligand binding by the associated receptors which leads to activation of additional tyrosine kinases and subsequent cell activation (By similarity). Also has an inhibitory role in some cells (By similarity). Non-covalently associates with activating receptors [...]	0.937
CSF1R	AIF1	ENSPTRP00000080883	ENSPTRP00000030665	Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	Allograft inflammatory factor 1.	0.613
CSF1R	FCER1G	ENSPTRP00000080883	ENSPTRP00000051638	Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	Fc fragment of IgE receptor Ig.	0.550
CSF1R	ITGB2	ENSPTRP00000080883	ENSPTRP00000091175	Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	Integrin beta.	0.601
CSF1R	TREM2	ENSPTRP00000080883	ENSPTRP00000031017	Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	Triggering receptor expressed on myeloid cells 2.	0.809
CSF1R	TYROBP	ENSPTRP00000080883	ENSPTRP00000018632	Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	TYRO protein tyrosine kinase-binding protein; Adapter protein which non-covalently associates with activating receptors found on the surface of a variety of immune cells to mediate signaling and cell activation following ligand binding by the receptors (By similarity). TYROBP is tyrosine-phosphorylated in the ITAM domain following ligand binding by the associated receptors which leads to activation of additional tyrosine kinases and subsequent cell activation (By similarity). Also has an inhibitory role in some cells (By similarity). Non-covalently associates with activating receptors [...]	0.940
FCER1G	AIF1	ENSPTRP00000051638	ENSPTRP00000030665	Fc fragment of IgE receptor Ig.	Allograft inflammatory factor 1.	0.876
FCER1G	CD300LB	ENSPTRP00000051638	ENSPTRP00000016328	Fc fragment of IgE receptor Ig.	CD300 molecule like family member b.	0.446
FCER1G	CD300LF	ENSPTRP00000051638	ENSPTRP00000016340	Fc fragment of IgE receptor Ig.	CD300 molecule like family member f.	0.512