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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZNF546Zinc finger protein 546. (836 aa)    
Predicted Functional Partners:
ZNF438
Zinc finger protein 438.
      
 0.735
MTA1
Metastasis associated 1.
    
 0.603
KRT83
Keratin, type II cuticular Hb3.
   
 0.594
OR8D2
OR8D2 isoform 1.
      
 0.579
KRT3
KRT3 isoform 1; Belongs to the intermediate filament family.
    
 0.557
SULT1C3
Sulfotransferase; Belongs to the sulfotransferase 1 family.
    
 
 0.515
OR2M7
Olfactory receptor.
      
 0.511
LRRK2
Leucine-rich repeat kinase 2.
    
 0.499
GSTZ1
Glutathione S-transferase zeta 1; Belongs to the GST superfamily.
    
 
 0.488
ADD1
ADD1 isoform 5.
      
 0.470
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.