STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAP3K10Mitogen-activated protein kinase kinase kinase. (954 aa)    
Predicted Functional Partners:
HTT
HTT isoform 1.
   
 0.914
EVI5L
Ecotropic viral integration site 5-like.
   
 
 0.805
MAPK8IP2
MAPK8IP2 isoform 2.
    
 
 0.698
CDC42
Cell division cycle 42 (GTP binding protein, 25kDa).
   
 0.626
MAPK8IP1
Mitogen-activated protein kinase 8 interacting protein 1.
    
 
 0.602
CNKSR1
CNKSR1 isoform 5.
    
 0.597
KIF3A
Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
 
 0.594
KIF3A-2
Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
 
 0.594
TAB1
TGF-beta activated kinase 1 (MAP3K7) binding protein 1.
  
 0.571
MIB2
Mindbomb homolog 2.
   
 0.557
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.