PVR protein (Pan troglodytes) - STRING interaction network

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[Homology]

Score

PVR

PVR cell adhesion molecule. (417 aa)

Predicted Functional Partners:

CD226

0.999

TIGIT

0.992

CD96

0.982

NECTIN3

0.970

ZNF395

0.812

TIMM50

0.742

NCR3

0.656

TOMM7-2

0.652

TOMM7

0.652

MGAT3

0.643

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD226	NCR3	ENSPTRP00000017164	ENSPTRP00000030663	CD226 isoform 1.	Natural cytotoxicity triggering receptor 3; Cell membrane receptor of natural killer/NK cells that is activated by binding of extracellular ligands including BAG6 and NCR3LG1. Stimulates NK cells cytotoxicity toward neighboring cells producing these ligands. It controls, for instance, NK cells cytotoxicity against tumor cells. Engagement of NCR3 by BAG6 also promotes myeloid dendritic cells (DC) maturation, both through killing DCs that did not acquire a mature phenotype, and inducing the release by NK cells of TNFA and IFNG that promote DC maturation.	0.763
CD226	PVR	ENSPTRP00000017164	ENSPTRP00000019082	CD226 isoform 1.	PVR cell adhesion molecule.	0.999
CD226	TIGIT	ENSPTRP00000017164	ENSPTRP00000026290	CD226 isoform 1.	TIGIT isoform 1.	0.856
CD96	NCR3	ENSPTRP00000026236	ENSPTRP00000030663	CD96 isoform 3.	Natural cytotoxicity triggering receptor 3; Cell membrane receptor of natural killer/NK cells that is activated by binding of extracellular ligands including BAG6 and NCR3LG1. Stimulates NK cells cytotoxicity toward neighboring cells producing these ligands. It controls, for instance, NK cells cytotoxicity against tumor cells. Engagement of NCR3 by BAG6 also promotes myeloid dendritic cells (DC) maturation, both through killing DCs that did not acquire a mature phenotype, and inducing the release by NK cells of TNFA and IFNG that promote DC maturation.	0.679
CD96	PVR	ENSPTRP00000026236	ENSPTRP00000019082	CD96 isoform 3.	PVR cell adhesion molecule.	0.982
CD96	TIGIT	ENSPTRP00000026236	ENSPTRP00000026290	CD96 isoform 3.	TIGIT isoform 1.	0.720
MGAT3	PVR	ENSPTRP00000024801	ENSPTRP00000019082	MGAT3 isoform 1.	PVR cell adhesion molecule.	0.643
MGAT3	TIMM50	ENSPTRP00000024801	ENSPTRP00000018812	MGAT3 isoform 1.	Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.	0.690
MGAT3	TOMM7	ENSPTRP00000024801	ENSPTRP00000061557	MGAT3 isoform 1.	Translocase of outer mitochondrial membrane 7 homolog.	0.744
MGAT3	TOMM7-2	ENSPTRP00000024801	ENSPTRP00000032434	MGAT3 isoform 1.	TOMM7 isoform 5.	0.744
NCR3	CD226	ENSPTRP00000030663	ENSPTRP00000017164	Natural cytotoxicity triggering receptor 3; Cell membrane receptor of natural killer/NK cells that is activated by binding of extracellular ligands including BAG6 and NCR3LG1. Stimulates NK cells cytotoxicity toward neighboring cells producing these ligands. It controls, for instance, NK cells cytotoxicity against tumor cells. Engagement of NCR3 by BAG6 also promotes myeloid dendritic cells (DC) maturation, both through killing DCs that did not acquire a mature phenotype, and inducing the release by NK cells of TNFA and IFNG that promote DC maturation.	CD226 isoform 1.	0.763
NCR3	CD96	ENSPTRP00000030663	ENSPTRP00000026236	Natural cytotoxicity triggering receptor 3; Cell membrane receptor of natural killer/NK cells that is activated by binding of extracellular ligands including BAG6 and NCR3LG1. Stimulates NK cells cytotoxicity toward neighboring cells producing these ligands. It controls, for instance, NK cells cytotoxicity against tumor cells. Engagement of NCR3 by BAG6 also promotes myeloid dendritic cells (DC) maturation, both through killing DCs that did not acquire a mature phenotype, and inducing the release by NK cells of TNFA and IFNG that promote DC maturation.	CD96 isoform 3.	0.679
NCR3	PVR	ENSPTRP00000030663	ENSPTRP00000019082	Natural cytotoxicity triggering receptor 3; Cell membrane receptor of natural killer/NK cells that is activated by binding of extracellular ligands including BAG6 and NCR3LG1. Stimulates NK cells cytotoxicity toward neighboring cells producing these ligands. It controls, for instance, NK cells cytotoxicity against tumor cells. Engagement of NCR3 by BAG6 also promotes myeloid dendritic cells (DC) maturation, both through killing DCs that did not acquire a mature phenotype, and inducing the release by NK cells of TNFA and IFNG that promote DC maturation.	PVR cell adhesion molecule.	0.656
NCR3	TIGIT	ENSPTRP00000030663	ENSPTRP00000026290	Natural cytotoxicity triggering receptor 3; Cell membrane receptor of natural killer/NK cells that is activated by binding of extracellular ligands including BAG6 and NCR3LG1. Stimulates NK cells cytotoxicity toward neighboring cells producing these ligands. It controls, for instance, NK cells cytotoxicity against tumor cells. Engagement of NCR3 by BAG6 also promotes myeloid dendritic cells (DC) maturation, both through killing DCs that did not acquire a mature phenotype, and inducing the release by NK cells of TNFA and IFNG that promote DC maturation.	TIGIT isoform 1.	0.578
NECTIN3	PVR	ENSPTRP00000075161	ENSPTRP00000019082	Poliovirus receptor-related 3.	PVR cell adhesion molecule.	0.970
NECTIN3	TIGIT	ENSPTRP00000075161	ENSPTRP00000026290	Poliovirus receptor-related 3.	TIGIT isoform 1.	0.975
PVR	CD226	ENSPTRP00000019082	ENSPTRP00000017164	PVR cell adhesion molecule.	CD226 isoform 1.	0.999
PVR	CD96	ENSPTRP00000019082	ENSPTRP00000026236	PVR cell adhesion molecule.	CD96 isoform 3.	0.982
PVR	MGAT3	ENSPTRP00000019082	ENSPTRP00000024801	PVR cell adhesion molecule.	MGAT3 isoform 1.	0.643
PVR	NCR3	ENSPTRP00000019082	ENSPTRP00000030663	PVR cell adhesion molecule.	Natural cytotoxicity triggering receptor 3; Cell membrane receptor of natural killer/NK cells that is activated by binding of extracellular ligands including BAG6 and NCR3LG1. Stimulates NK cells cytotoxicity toward neighboring cells producing these ligands. It controls, for instance, NK cells cytotoxicity against tumor cells. Engagement of NCR3 by BAG6 also promotes myeloid dendritic cells (DC) maturation, both through killing DCs that did not acquire a mature phenotype, and inducing the release by NK cells of TNFA and IFNG that promote DC maturation.	0.656