STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLA2G4CPhospholipase A2 group IVC. (541 aa)    
Predicted Functional Partners:
PLA2G2A
Phospholipase A(2).
     
 0.921
NFATC2IP
Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein.
      
 0.900
RNF11
Ring finger protein 11.
   
  
 0.812
NUAK2
NUAK2 isoform 1.
      
 0.752
FITM1
Fat storage-inducing transmembrane protein 1.
      
 0.697
DGAT1
O-acyltransferase.
   
  
 0.696
RIPK2
Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains.
    
 0.674
HPGD
15-hydroxyprostaglandin dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
  
 0.624
CILP2
Cartilage intermediate layer protein 2.
      
 0.619
ENSPTRP00000062605
annotation not available
      
 0.619
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.