STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DKKL1Dickkopf like acrosomal protein 1. (242 aa)    
Predicted Functional Partners:
SIPA1L3
Signal induced proliferation associated 1 like 3.
      
 0.784
DAGLA
Diacylglycerol lipase, alpha.
      
 0.772
CCDC155
Coiled-coil domain containing 155.
  
  
 0.747
PGBD1
PiggyBac transposable element derived 1.
     
 0.689
KCNC3
KCNC3 isoform 4; Belongs to the potassium channel family.
      
 0.669
LRP5
Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.
    
 0.634
WNT2B
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.
   
  
 0.582
DKK1
Dickkopf-like protein 1.
      
 0.577
CAGE1
Cancer antigen 1.
      
 0.577
RAB11B
RAB11B, member RAS oncogene family.
     
 0.567
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.