STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTOV1PTOV1 extended AT-hook containing adaptor protein. (452 aa)    
Predicted Functional Partners:
FANCM
Fanconi anemia, complementation group M.
   
 0.788
FLOT1
Flotillin-1; May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles.
    
 
 0.697
MED6
Mediator of RNA polymerase II transcription subunit 6; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
 0.664
FLOT2
Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily.
    
 
 0.599
CREBBP
CREB binding protein.
   
 0.536
KLHDC2
Kelch domain containing 2.
    
 
 0.521
CENPT
Centromere protein T.
    
 0.461
LIN9
LIN9 isoform 3.
    
 0.423
NCOR2
Nuclear receptor corepressor 2.
   
 0.418
MEIOB
MEIOB isoform 2.
    
 0.410
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.