STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KLK4Kallikrein related peptidase 4; Belongs to the peptidase S1 family. (254 aa)    
Predicted Functional Partners:
MMP20
Matrix metallopeptidase 20.
   
 0.917
SERPING1
Serpin peptidase inhibitor, clade G (C1 inhibitor), member 1; Belongs to the serpin family.
    
 0.913
KNG1
KNG1 isoform 2.
   
 0.902
TUFT1
TUFT1 isoform 2.
      
 0.869
A2M
Alpha-2-macroglobulin.
    
 0.857
ODAM
Odontogenic ameloblast-associated protein; Tooth-associated epithelia protein that probably plays a role in odontogenesis, the complex process that results in the initiation and generation of the tooth. May be incorporated in the enamel matrix at the end of mineralization process. Involved in the induction of RHOA activity via interaction with ARHGEF and expression of downstream factors such as ROCK. Plays a role in attachment of the junctional epithelium to the tooth surface; Belongs to the ODAM family.
      
 0.848
WDR72
WD repeat domain 72.
      
 0.777
ENAM
ENAM isoform 1.
      
 0.773
DMP1
Dentin matrix acidic phosphoprotein 1.
    
 
 0.764
AMTN
AMTN isoform 1.
      
 0.743
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.