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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PUM2Pumilio RNA binding family member 2. (1065 aa)    
Predicted Functional Partners:
NANOS1
Nanos C2HC-type zinc finger 1; Belongs to the nanos family.
   
 
 0.956
ATXN1
ATXN1 isoform 2.
     
 0.906
ATXN1L
ATXN1L isoform 2.
     
 0.903
DAZL
RRM domain-containing protein.
    
 
 0.873
ENSPTRP00000048401
Deleted in azoospermia protein 1 isoform X1.
    
 
 0.792
GAK
Cyclin G associated kinase.
   
 0.784
KHSRP
KHSRP isoform 2.
   
 
 0.734
BOLL
BOLL isoform 3.
   
 
 0.721
AGO2
Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]
   
 
 0.702
MOV10
Mov10, Moloney leukemia virus 10, homolog.
   
 
 0.692
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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