STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ITSN2ITSN2 isoform 1. (1684 aa)    
Predicted Functional Partners:
FCHO1
FCHO1 isoform 7.
   
 0.995
EPS15
Epidermal growth factor receptor pathway substrate 15.
   
0.994
EPS15L1
Epidermal growth factor receptor pathway substrate 15 like 1.
   
0.992
FCHO2
FCH domain only 2.
   
 0.988
WASL
WASP like actin nucleation promoting factor.
    
 0.986
CDC42
Cell division cycle 42 (GTP binding protein, 25kDa).
    
 0.986
AP2M1
AP2M1 isoform 3; Belongs to the adaptor complexes medium subunit family.
    
 0.985
AP2S1
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
   
 0.982
GAS7
Growth arrest-specific 7.
   
 0.979
AP4B1
AP complex subunit beta; Belongs to the adaptor complexes large subunit family.
    
 0.978
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.