STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PPM1BProtein phosphatase, Mg2+/Mn2+ dependent, 1B. (479 aa)    
Predicted Functional Partners:
CK820_G0054574
ISG15 isoform 1.
   
 0.924
ISG15
ISG15 ubiquitin-like modifier.
   
 0.924
MAP3K7
Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
  
 0.921
PREPL
Prolyl endopeptidase-like.
   
  
 0.775
SLC3A1
Solute carrier family 3 member 1.
 
 
  
 0.747
CAMKMT
Calmodulin-lysine N-methyltransferase.
      
 0.723
GHRH
Growth hormone releasing hormone.
   
    0.701
CHUK
Component of inhibitor of nuclear factor kappa B kinase complex.
  
 0.668
PPP2CB
Serine/threonine-protein phosphatase.
   
 
 0.637
MLKL
Mixed lineage kinase domain like pseudokinase.
   
 0.629
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.