STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EPAS1Endothelial PAS domain protein 1. (870 aa)    
Predicted Functional Partners:
ARNT
Aryl hydrocarbon receptor nuclear translocator.
   
0.999
VHL
Von Hippel-Lindau tumor suppressor.
    
 0.999
EGLN1
EGLN1 isoform 1.
    
 0.998
HIF1A
Hypoxia inducible factor 1 subunit alpha.
   
0.997
ARNT2
ARNT2 isoform 2.
   
0.994
EP300
E1A binding protein p300.
    
 0.992
EGLN2
T0107007 isoform 1.
    
 0.990
LOC107968511
Elongin-C-like.
    
 0.987
ELOC
Transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C); Belongs to the SKP1 family.
    
 0.987
ENSPTRP00000060850
Elongin-B-like.
    
 0.986
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.