STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MSH6DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1360 aa)    
Predicted Functional Partners:
MLH1
MutL homolog 1, colon cancer, nonpolyposis type 2.
 
 0.999
MSH2
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
   
0.999
MSH3
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
  
 
0.995
PMS1
PMS1 homolog 1, mismatch repair system component.
 
 0.991
PMS2
PMS1 homolog 2, mismatch repair system component.
  
 0.991
EXO1
EXO1 isoform 1.
   
 0.986
MLH3
MLH3 isoform 1.
  
 0.974
CK820_G0052740
PMS2 isoform 6.
  
 0.968
CK820_G0047513
Uncharacterized protein.
  
 0.968
PCNA
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.957
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.