LHCGR protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FSHB	GNB1	ENSPTRP00000006017	ENSPTRP00000067330	Follitropin subunit beta; Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs.	Guanine nucleotide binding protein (G protein), beta polypeptide 1.	0.606
FSHB	GNB4	ENSPTRP00000006017	ENSPTRP00000026924	Follitropin subunit beta; Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs.	Guanine nucleotide binding protein (G protein), beta polypeptide 4.	0.431
FSHB	GNG2	ENSPTRP00000006017	ENSPTRP00000065345	Follitropin subunit beta; Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.618
FSHB	GNG4	ENSPTRP00000006017	ENSPTRP00000003602	Follitropin subunit beta; Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.445
FSHB	LHCGR	ENSPTRP00000006017	ENSPTRP00000020451	Follitropin subunit beta; Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs.	Lutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.	0.970
GNAS	GNB1	ENSPTRP00000059419	ENSPTRP00000067330	GNAS isoform 19.	Guanine nucleotide binding protein (G protein), beta polypeptide 1.	0.996
GNAS	GNB2	ENSPTRP00000059419	ENSPTRP00000085287	GNAS isoform 19.	Guanine nucleotide binding protein (G protein), beta polypeptide 2.	0.951
GNAS	GNB3	ENSPTRP00000059419	ENSPTRP00000045189	GNAS isoform 19.	G protein subunit beta 3.	0.970
GNAS	GNB4	ENSPTRP00000059419	ENSPTRP00000026924	GNAS isoform 19.	Guanine nucleotide binding protein (G protein), beta polypeptide 4.	0.989
GNAS	GNB5	ENSPTRP00000059419	ENSPTRP00000012110	GNAS isoform 19.	GNB5 isoform 1.	0.966
GNAS	GNG2	ENSPTRP00000059419	ENSPTRP00000065345	GNAS isoform 19.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.995
GNAS	GNG4	ENSPTRP00000059419	ENSPTRP00000003602	GNAS isoform 19.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.994
GNAS	LHCGR	ENSPTRP00000059419	ENSPTRP00000020451	GNAS isoform 19.	Lutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.	0.953
GNB1	FSHB	ENSPTRP00000067330	ENSPTRP00000006017	Guanine nucleotide binding protein (G protein), beta polypeptide 1.	Follitropin subunit beta; Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs.	0.606
GNB1	GNAS	ENSPTRP00000067330	ENSPTRP00000059419	Guanine nucleotide binding protein (G protein), beta polypeptide 1.	GNAS isoform 19.	0.996
GNB1	GNB2	ENSPTRP00000067330	ENSPTRP00000085287	Guanine nucleotide binding protein (G protein), beta polypeptide 1.	Guanine nucleotide binding protein (G protein), beta polypeptide 2.	0.963
GNB1	GNB3	ENSPTRP00000067330	ENSPTRP00000045189	Guanine nucleotide binding protein (G protein), beta polypeptide 1.	G protein subunit beta 3.	0.990
GNB1	GNB4	ENSPTRP00000067330	ENSPTRP00000026924	Guanine nucleotide binding protein (G protein), beta polypeptide 1.	Guanine nucleotide binding protein (G protein), beta polypeptide 4.	0.997
GNB1	GNB5	ENSPTRP00000067330	ENSPTRP00000012110	Guanine nucleotide binding protein (G protein), beta polypeptide 1.	GNB5 isoform 1.	0.962
GNB1	GNG2	ENSPTRP00000067330	ENSPTRP00000065345	Guanine nucleotide binding protein (G protein), beta polypeptide 1.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.999