| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| FSHB | FSHR | ENSPTRP00000006017 | ENSPTRP00000020457 | Follitropin subunit beta; Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs. | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. | 0.998 |
| FSHB | GNB1 | ENSPTRP00000006017 | ENSPTRP00000067330 | Follitropin subunit beta; Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs. | Guanine nucleotide binding protein (G protein), beta polypeptide 1. | 0.606 |
| FSHB | GNB4 | ENSPTRP00000006017 | ENSPTRP00000026924 | Follitropin subunit beta; Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs. | Guanine nucleotide binding protein (G protein), beta polypeptide 4. | 0.431 |
| FSHB | GNG2 | ENSPTRP00000006017 | ENSPTRP00000065345 | Follitropin subunit beta; Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs. | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | 0.618 |
| FSHB | GNG4 | ENSPTRP00000006017 | ENSPTRP00000003602 | Follitropin subunit beta; Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs. | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | 0.445 |
| FSHB | TSHB | ENSPTRP00000006017 | ENSPTRP00000001962 | Follitropin subunit beta; Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs. | Thyroid stimulating hormone subunit beta. | 0.469 |
| FSHR | FSHB | ENSPTRP00000020457 | ENSPTRP00000006017 | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. | Follitropin subunit beta; Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs. | 0.998 |
| FSHR | GNAS | ENSPTRP00000020457 | ENSPTRP00000059419 | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. | GNAS isoform 19. | 0.945 |
| FSHR | GNB1 | ENSPTRP00000020457 | ENSPTRP00000067330 | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. | Guanine nucleotide binding protein (G protein), beta polypeptide 1. | 0.973 |
| FSHR | GNB2 | ENSPTRP00000020457 | ENSPTRP00000085287 | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. | Guanine nucleotide binding protein (G protein), beta polypeptide 2. | 0.943 |
| FSHR | GNB3 | ENSPTRP00000020457 | ENSPTRP00000045189 | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. | G protein subunit beta 3. | 0.925 |
| FSHR | GNB4 | ENSPTRP00000020457 | ENSPTRP00000026924 | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. | Guanine nucleotide binding protein (G protein), beta polypeptide 4. | 0.957 |
| FSHR | GNB5 | ENSPTRP00000020457 | ENSPTRP00000012110 | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. | GNB5 isoform 1. | 0.923 |
| FSHR | GNG2 | ENSPTRP00000020457 | ENSPTRP00000065345 | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | 0.958 |
| FSHR | GNG4 | ENSPTRP00000020457 | ENSPTRP00000003602 | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | 0.939 |
| FSHR | TSHB | ENSPTRP00000020457 | ENSPTRP00000001962 | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. | Thyroid stimulating hormone subunit beta. | 0.931 |
| GNAS | FSHR | ENSPTRP00000059419 | ENSPTRP00000020457 | GNAS isoform 19. | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. | 0.945 |
| GNAS | GNB1 | ENSPTRP00000059419 | ENSPTRP00000067330 | GNAS isoform 19. | Guanine nucleotide binding protein (G protein), beta polypeptide 1. | 0.996 |
| GNAS | GNB2 | ENSPTRP00000059419 | ENSPTRP00000085287 | GNAS isoform 19. | Guanine nucleotide binding protein (G protein), beta polypeptide 2. | 0.951 |
| GNAS | GNB3 | ENSPTRP00000059419 | ENSPTRP00000045189 | GNAS isoform 19. | G protein subunit beta 3. | 0.970 |
