STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DOK1Docking protein 1, 62kDa (Downstream of tyrosine kinase 1). (481 aa)    
Predicted Functional Partners:
RASA1
RAS p21 protein activator (GTPase activating protein) 1.
    
 
 0.958
PTK6
Tyrosine-protein kinase.
    
 0.901
CK820_G0012168
ABL1 isoform 3.
    
 0.843
ABL1
Tyrosine-protein kinase.
    
 0.843
RET
Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.
    
  0.797
CSK
Tyrosine-protein kinase.
    
 0.780
NCK1
Cytoplasmic protein.
    
 
 0.715
NCK2
Cytoplasmic protein.
    
 
 0.693
CRKL
V-crk sarcoma virus CT10 oncogene homolog (Avian)-like.
    
 0.682
ENSPTRP00000089450
annotation not available
    
 0.682
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.