STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TCF7L1Transcription factor 7 like 1. (587 aa)    
Predicted Functional Partners:
CTNNB1
Catenin (Cadherin-associated protein), beta 1, 88kDa.
    
 0.972
LEO1
Leo1, Paf1/RNA polymerase II complex component, homolog.
     
 0.836
TCF7L2
Transcription factor 7 like 2.
     
0.821
LEF1
Lymphoid enhancer binding factor 1.
  
 
0.798
NLK
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
    
 0.793
TCF7
Transcription factor 7.
     
0.783
JUP
Junction plakoglobin.
    
 0.763
EP300
E1A binding protein p300.
   
 0.751
TLE1
Transducin-like enhancer of split 1.
    
 0.749
DVL2
Dishevelled segment polarity protein 2.
      
 0.728
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.