GGCX protein (Pan troglodytes) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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Assay-based Predictions

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co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BGLAP	GGCX	ENSPTRP00000002450	ENSPTRP00000020816	Osteocalcin; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium.	Gamma-glutamyl carboxylase.	0.925
BGLAP	MGP	ENSPTRP00000002450	ENSPTRP00000090622	Osteocalcin; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium.	Matrix Gla protein; Associates with the organic matrix of bone and cartilage.	0.523
ENSPTRP00000062265	GGCX	ENSPTRP00000062265	ENSPTRP00000020816	annotation not available	Gamma-glutamyl carboxylase.	0.925
ENSPTRP00000062265	MGP	ENSPTRP00000062265	ENSPTRP00000090622	annotation not available	Matrix Gla protein; Associates with the organic matrix of bone and cartilage.	0.523
F2	F9	ENSPTRP00000006168	ENSPTRP00000047240	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Coagulation factor IXa heavy chain; Factor IX is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca(2+) ions, phospholipids, and factor VIIIa; Belongs to the peptidase S1 family.	0.740
F2	GGCX	ENSPTRP00000006168	ENSPTRP00000020816	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Gamma-glutamyl carboxylase.	0.963
F2	PROC	ENSPTRP00000006168	ENSPTRP00000064418	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Protein C, inactivator of coagulation factors Va and VIIIa.	0.986
F2	VKORC1	ENSPTRP00000006168	ENSPTRP00000013718	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Vitamin K epoxide reductase complex subunit 1 precursor.	0.587
F9	F2	ENSPTRP00000047240	ENSPTRP00000006168	Coagulation factor IXa heavy chain; Factor IX is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca(2+) ions, phospholipids, and factor VIIIa; Belongs to the peptidase S1 family.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.740
F9	GGCX	ENSPTRP00000047240	ENSPTRP00000020816	Coagulation factor IXa heavy chain; Factor IX is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca(2+) ions, phospholipids, and factor VIIIa; Belongs to the peptidase S1 family.	Gamma-glutamyl carboxylase.	0.947
F9	PROC	ENSPTRP00000047240	ENSPTRP00000064418	Coagulation factor IXa heavy chain; Factor IX is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca(2+) ions, phospholipids, and factor VIIIa; Belongs to the peptidase S1 family.	Protein C, inactivator of coagulation factors Va and VIIIa.	0.509
F9	VKORC1	ENSPTRP00000047240	ENSPTRP00000013718	Coagulation factor IXa heavy chain; Factor IX is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca(2+) ions, phospholipids, and factor VIIIa; Belongs to the peptidase S1 family.	Vitamin K epoxide reductase complex subunit 1 precursor.	0.515
GGCX	BGLAP	ENSPTRP00000020816	ENSPTRP00000002450	Gamma-glutamyl carboxylase.	Osteocalcin; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium.	0.925
GGCX	ENSPTRP00000062265	ENSPTRP00000020816	ENSPTRP00000062265	Gamma-glutamyl carboxylase.	annotation not available	0.925
GGCX	F2	ENSPTRP00000020816	ENSPTRP00000006168	Gamma-glutamyl carboxylase.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.963
GGCX	F9	ENSPTRP00000020816	ENSPTRP00000047240	Gamma-glutamyl carboxylase.	Coagulation factor IXa heavy chain; Factor IX is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca(2+) ions, phospholipids, and factor VIIIa; Belongs to the peptidase S1 family.	0.947
GGCX	MGP	ENSPTRP00000020816	ENSPTRP00000090622	Gamma-glutamyl carboxylase.	Matrix Gla protein; Associates with the organic matrix of bone and cartilage.	0.908
GGCX	NQO1	ENSPTRP00000020816	ENSPTRP00000014148	Gamma-glutamyl carboxylase.	NAD(P)H quinone dehydrogenase 1.	0.953
GGCX	PROC	ENSPTRP00000020816	ENSPTRP00000064418	Gamma-glutamyl carboxylase.	Protein C, inactivator of coagulation factors Va and VIIIa.	0.952
GGCX	PRRG2	ENSPTRP00000020816	ENSPTRP00000019405	Gamma-glutamyl carboxylase.	Proline rich and Gla domain 2.	0.878