STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CIAO1Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation; Belongs to the WD repeat CIA1 family. (345 aa)    
Predicted Functional Partners:
MMS19
MMS19 isoform 2.
    
 0.998
CIAO2B
Cytosolic iron-sulfur assembly component 2B.
    
 0.998
CIAO2A
FAM96A isoform 1.
    
 0.977
CIAO3
Nuclear prelamin A recognition factor-like; Belongs to the NARF family.
    
 0.948
ENSPTRP00000093111
annotation not available
    
 0.943
DCAF10
DDB1 and CUL4 associated factor 10.
    
 
 0.907
C17H17orf75
Chromosome 17 open reading frame 75.
      
 0.905
RAB3IP
T0146196 isoform 1.
      
 0.889
CYP20A1
Cytochrome P450, family 20, subfamily A, polypeptide 1.
      
 0.884
SYNJ2BP
Synaptojanin 2 binding protein.
      
 0.872
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.