STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZAP70Tyrosine-protein kinase. (619 aa)    
Predicted Functional Partners:
CD247
CD247 isoform 2.
   
 0.999
CD3E
CD3E isoform 2.
   
 0.998
LCP2
Lymphocyte cytosolic protein 2.
   
 0.998
LAT
Linker for activation of T cells.
   
 0.998
CBL
Cas-Br-M (Murine) ecotropic retroviral transforming sequence.
    
 0.996
VAV1
Vav guanine nucleotide exchange factor 1.
   
 0.995
LCK
Tyrosine-protein kinase.
   
0.994
CBLB
Cas-Br-M (Murine) ecotropic retroviral transforming sequence b.
    
 0.994
CD3G
CD3G isoform 1.
   
 0.990
SHC1
SHC (Src homology 2 domain containing) transforming protein 1.
   
 0.989
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.