STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RNF149Ring finger protein 149. (400 aa)    
Predicted Functional Partners:
TRIP12
Thyroid hormone receptor interactor 12.
   
 
 0.461
TNFRSF10B
TNF receptor superfamily member 10b.
    
   0.456
KXD1
UBA52 isoform 10.
    
 0.451
ENSPTRP00000067263
Ubiquitin-large subunit ribosomal protein L40e.
    
 0.451
ENSPTRP00000071568
annotation not available
    
 0.451
RNF128
Ring finger protein 128.
   
0.448
ACVR1
Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
    
   0.446
UBE2O
Ubiquitin conjugating enzyme E2 O.
   
 0.415
RXFP2
Relaxin family peptide receptor 2.
    
 0.408
RXFP1
RXFP1 isoform 5.
    
 0.408
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.