STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RFX8RFX8 isoform 3. (454 aa)    
Predicted Functional Partners:
PIGQ
Phosphatidylinositol glycan anchor biosynthesis class Q.
      
 0.765
LRRTM4
LRRTM4 isoform 3.
      
 0.762
LLPH
LLP homolog, long-term synaptic facilitation (Aplysia).
      
 0.733
ACSS3
Acyl-CoA synthetase short-chain family member 3.
      
 0.728
THOC1
THOC1 isoform 2.
      
 0.707
ASIC2
Acid sensing ion channel subunit 2; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
    
 
 0.692
MSRB3
Peptide-methionine (R)-S-oxide reductase; Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues.
      
 0.642
ATR
Ataxia telangiectasia and Rad3 related; Belongs to the PI3/PI4-kinase family.
    
 
 0.563
CHEK2
Checkpoint kinase 2.
   
 
 0.519
MEIS1
MEIS1 isoform 7.
      
 0.515
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.