STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NPHP1NPHP1 isoform 1. (729 aa)    
Predicted Functional Partners:
NPHP4
NPHP4 isoform 5.
   
 0.998
RPGRIP1L
RPGRIP1L isoform 4.
    
 0.993
TMEM67
Transmembrane protein 67.
   
  
 0.842
AHI1
Abelson helper integration site 1.
    
 0.839
INVS
INVS isoform 1.
    
 0.825
CEP290
CEP290 isoform 5.
   
 0.813
RPGR
RPGR isoform 3.
    
 
 0.810
BCAR1
BCAR1 scaffold protein, Cas family member.
    
 
 0.752
IQCB1
IQ motif containing B1.
    
 0.747
RPGRIP1
RPGR interacting protein 1.
    
 0.742
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.