IL1F10 protein (Pan troglodytes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pan troglodytes

NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD4	IL1F10	ENSPTRP00000054833	ENSPTRP00000021198	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	Interleukin-1.	0.625
CD4	IL1R1	ENSPTRP00000054833	ENSPTRP00000075043	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	Interleukin 1 receptor, type I.	0.520
CD4	IL1RL2	ENSPTRP00000054833	ENSPTRP00000021069	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	IL1RL2 isoform 1.	0.520
IL18RAP	IL1F10	ENSPTRP00000021078	ENSPTRP00000021198	Interleukin 18 receptor accessory protein.	Interleukin-1.	0.834
IL18RAP	LY96	ENSPTRP00000021078	ENSPTRP00000083213	Interleukin 18 receptor accessory protein.	Lymphocyte antigen 96.	0.749
IL1F10	CD4	ENSPTRP00000021198	ENSPTRP00000054833	Interleukin-1.	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	0.625
IL1F10	IL18RAP	ENSPTRP00000021198	ENSPTRP00000021078	Interleukin-1.	Interleukin 18 receptor accessory protein.	0.834
IL1F10	IL1R1	ENSPTRP00000021198	ENSPTRP00000075043	Interleukin-1.	Interleukin 1 receptor, type I.	0.876
IL1F10	IL1RAP	ENSPTRP00000021198	ENSPTRP00000083273	Interleukin-1.	Interleukin 1 receptor accessory protein.	0.959
IL1F10	IL1RAPL1	ENSPTRP00000021198	ENSPTRP00000037316	Interleukin-1.	Interleukin-1 receptor accessory protein-like 1; May regulate secretion and presynaptic differentiation through inhibition of the activity of N-type voltage-gated calcium channel. May activate the MAP kinase JNK (By similarity). Plays a role in neurite outgrowth (By similarity). During dendritic spine formation can bidirectionally induce pre- and post-synaptic differentiation of neurons by trans-synaptically binding to PTPRD (By similarity).	0.892
IL1F10	IL1RAPL2	ENSPTRP00000021198	ENSPTRP00000038081	Interleukin-1.	Interleukin 1 receptor accessory protein like 2.	0.709
IL1F10	IL1RL2	ENSPTRP00000021198	ENSPTRP00000021069	Interleukin-1.	IL1RL2 isoform 1.	0.993
IL1F10	LY96	ENSPTRP00000021198	ENSPTRP00000083213	Interleukin-1.	Lymphocyte antigen 96.	0.620
IL1F10	MEFV	ENSPTRP00000021198	ENSPTRP00000013131	Interleukin-1.	MEFV isoform 5.	0.610
IL1F10	MEFV-2	ENSPTRP00000021198	ENSPTRP00000082153	Interleukin-1.	MEFV isoform 4.	0.610
IL1R1	CD4	ENSPTRP00000075043	ENSPTRP00000054833	Interleukin 1 receptor, type I.	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	0.520
IL1R1	IL1F10	ENSPTRP00000075043	ENSPTRP00000021198	Interleukin 1 receptor, type I.	Interleukin-1.	0.876
IL1R1	IL1RAP	ENSPTRP00000075043	ENSPTRP00000083273	Interleukin 1 receptor, type I.	Interleukin 1 receptor accessory protein.	0.996
IL1RAP	IL1F10	ENSPTRP00000083273	ENSPTRP00000021198	Interleukin 1 receptor accessory protein.	Interleukin-1.	0.959
IL1RAP	IL1R1	ENSPTRP00000083273	ENSPTRP00000075043	Interleukin 1 receptor accessory protein.	Interleukin 1 receptor, type I.	0.996