STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IL1F10Interleukin-1. (152 aa)    
Predicted Functional Partners:
IL1RL2
IL1RL2 isoform 1.
   
 0.998
IL1RAP
Interleukin 1 receptor accessory protein.
   
 
 0.960
IL1RAPL1
Interleukin-1 receptor accessory protein-like 1; May regulate secretion and presynaptic differentiation through inhibition of the activity of N-type voltage-gated calcium channel. May activate the MAP kinase JNK (By similarity). Plays a role in neurite outgrowth (By similarity). During dendritic spine formation can bidirectionally induce pre- and post-synaptic differentiation of neurons by trans-synaptically binding to PTPRD (By similarity).
     
 0.942
IL1R1
Interleukin 1 receptor, type I.
   
 0.889
IL18RAP
Interleukin 18 receptor accessory protein.
   
 0.853
IL18R1
Uncharacterized protein.
   
 0.687
IL1RAPL2
Interleukin 1 receptor accessory protein like 2.
     
 0.684
LY96
Lymphocyte antigen 96.
   
  
 0.680
MPO
Myeloperoxidase.
   
  
 0.668
KPNA7
Importin subunit alpha; Functions in nuclear protein import.
      
 0.661
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.