STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TFCP2L1Transcription factor CP2 like 1. (479 aa)    
Predicted Functional Partners:
LYPD1
LY6/PLAUR domain containing 1.
      
 0.812
RAB3B
RAB3B, member RAS oncogene family.
   
  
 0.762
GLI2
GLI family zinc finger 2.
    
 
 0.709
FZD5
Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 
 0.679
MYLK2
MYLK2 isoform 1.
      
 0.656
INHBB
Inhibin subunit beta B.
      
 0.630
ESRRB
Estrogen related receptor beta.
    
 0.618
FOXS1
FOXS1 isoform 1.
   
 
 0.594
CYP11A1
Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]
   
 
 0.576
TFCP2
Transcription factor CP2.
  
 
 
0.506
Your Current Organism:
Pan troglodytes
NCBI taxonomy Id: 9598
Other names: P. troglodytes, chimpanzee
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.